Amyloidosis is a rare condition that occurs when a substance of abnormally folded proteins called amyloids are deposited in various organs and cause damage by displacing normal cells.
Primarily the condition affects the kidneys, but it can also be present in other organs including the spleen, intestines, stomach and heart.
The main symptoms can be linked to kidney failure which include lethargy, dehydration, gingivitis, lack of appetite and weight loss. Kidney failure occurs because the kidneys become enlarged and inflamed as normal tissue is displaced by the amyloids and so they can no longer filter toxic waste from the body or reabsorb valuable amino acids and proteins.
The condition is rarely reported but it is more commonly found in Abyssinian cats than in any other cat breed. If you’re considering buying an Abyssinian, you must check that the cat’s family has no history of amyloidosis as it can be inherited.
Amyloidosis is generally developed between the ages of one and five with progression varying in each case from slow to rapid.